On the website cars.com, when viewing a single vehicle listing, clicking the plus sign/zoom for an image (visible on cursor hover) does nothing unless the "Enable Content Blockers" is unchecked in Website Settings.
Seems like there is an overly aggresive blocking of site resources/assets (one same domain file can be seen in the list of blocked files.)
This same behavior also occurs in Safari, so it's not an uncommon issue.
Clicking the plus sign icon should allow the gallery popup to open even when Content Blockers are enabled.
A suggestion is to allow the ability to whitelist certain files found in the Privacy Report requests blocked list.
Mockups:
Version 0.99.130-beta (WebKit 621.1.2.111.4)/macOS 15.2 (24C101)
Sequoia (15)