If you deny the Mac OS camera/mic prompt for Orion (trigger one from https://zoom.us/test and go to start a test call), then there is no obvious way to see Orion has no access to camera/mic. A user may think this is a website request they denied, therefore meaning there's no easy way to get back and fix this.
One option might be to "pre-prompt" the user (as Orion) and only pop the system prompt if they accept? That way they can always get another "bite" of the cherry.
Or perhaps when attempts are made to use camera/mic, Orion should prompt the user via a popup, say they have no access, and guide them to system preferences to fix?
I almost flagged this as a bug, since I thought there was a genuine bug with ask/allow/deny on per-site webcam/mic permissions until I diagnosed that it was system-level blocking.
Similarly (perhaps a bug), I don't think Orion should request the permission from the OS before you agree to let a website access them - if the user denies the website in question permission, they don't want to use camera/mic on that site, so it isn't a good time to prompt them for an Orion-level system prompt for access.