I love Orion, and for most sites that refuse to work with an ad blocker I just shrug and close the page: their loss.
But there are a few exceptions, notable YouTube. Even with content blocking disabled, it is sometimes (intermittently) popping up an angry "turn off your ad blocker!" screen. I'm willing to watch the ads there, but I suspect they are really trying to do some sort of tracking, and I'm unwilling to turn that off in my main browser.
I'm thinking of setting up finicky, but that's old and unmaintained, and it occurs to me that what I really want is for this to be a browser feature.
So a suggestion: allow the user to configure, for specific websites, a redirect out to Chrome -- ideally a specific Chrome profile. That would allow me to watch YouTube the way it wants to be watched, but in a nicely sandboxed environment where it can't do much harm.
I don't know of any real browsers that do this, but the finicky project, linked above, is a good, fully-worked illustration of the core idea. (We used this at my workplace a while back, for a project where we needed to be actively managing different aspects in different browsers.)
