I am having the same problem with the latest RC [0.99.126.4.1.5-rc (WebKit 619.1.1)] (testing on Catalina). The issue appears to be links that redirect. I can reproduce easily with Google -- if I search for webkit and then click on the link to the Webkit.org site, I get a refresh of the search results. If I just type in webkit.org, it goes right to the site.
I occasionally experienced something like this with earlier beta versions where after a while if I had a lot of tabs open and then tried to open a link in a new tab, it would just refresh the page. If I restarted Orion, everything went back to normal. The issue with this RC is a little different -- once in a website, right-clicking on a link to open in a new tab seems to work fine. But every time I do a regular click on a link from Google search results to open it, Orion just refreshes the window.