Steps to reproduce:
Install the SponsorBlock extension - this extension is used to skip crowdsourced segments on YouTube videos (e.g. sponsor segments)
Go to YouTube.com
If the extension would work correctly, the first two icons on the left would show up on the controls bar at the bottom of the video
Segments flagged to be skipped also get a different colour on the video's progress bar
Right now on Orion the extension doesn't work, but it did (partially) just before the .109 update.
Orion and macOS:
Version 0.99.109-beta (WebKit 613.1.12)