Saw this and wanted to jump in because last time I tried MetaMask in Orion it did not work at all.
Today, I was able to install MetaMask (the firefox extension), import my account, add new accounts, switch networks, and interact with my metamask wallet as expected (deploy contracts, call contracts, send eth) through remix. I also was able to connect through the extension to a couple testnet faucets.
Not sure what issues Joxy is facing, or which sites aren't working; but for me MetaMask seems to be fully functional.
Orion Version 0.99.120.1-beta (WebKit 614.1.20)
MacBook Pro (macOS Monterey 12.5.1 build 21G83)