Steps to reproduce:
I cannot reproduce it always but in most tabs all extension buttons in toolbar are working. But for some tabs, clicking on the buttons does not make anything. They seems to be dead. In extension settings shown for example extensions in the video there are no restrictions ("Always Allow on Every Website" is set).
Expected behavior:
Buttons should always work.
Orion, OS version; hardware type:
Orion Version 0.99.111-beta (WebKit 613.1.12)
macOS 12.1
Image/Video: