It would be great if Orion had something similar to Arc's Air Traffic. Basically you can define a URL condition and set in which profile it should open. It's really the only thing I'm missing from Orion.
I have different profiles for personal and work stuff, mainly because I use some of the same services (thing Google) in both areas, but with different accounts. For this reason, in Arc I set up a rule to open Google Meet links in my Work profile, because if I'm doing a Meet, it's always work related. Just an example.