I understand that vanilla uBlock Origin is not supported on Orion for iOS because of WebKit restrictions, however, uBlock Origin Lite has been supported on Safari since iOS 18.6, with Apple fixing a lot of bugs with declarativeNetRequest on Safari.
Unfortunately, uBOL still doesn't work on Orion for iOS with declarativeNetRequest not being supported. It would be great if Orion for iOS could have parity with Safari.

In my experience, uBOL does a much better job of blocking ads compared to content blockers.